Nederlandse perspectieven op de duurzaamheid van biomassa - Resultaten van interviews met stakeholders in het kader van de Biomassadialoog

In Dutch: Nederlandse perspectieven op de duurzaamheid van biomassa: Resultaten van de interviews met stakeholders in het kader van de Biomassadialoo

DELIVERABLE: D5.1 MONITORING AND VALIDATION STRATEGIES

This deliverable report will present the strategies developed for monitoring the case study demonstrations to be undertaken as part of WP4. The strategies presented will include both methods for quantitative validation, including data capture and relevant KPIs, and those catering for more qualitative evaluation using aspects such as contextual interviews, self-observations, and/or questionnaires.This work is part of the DR BOB Project. The DR-BOB Collaborative Project (Grant Agreement No. 696114) is co-funded by the European Commission, Information Society and Media Directorate-General, under the Horizon 2020 Programme (H2020)

Religious Experience and the Modernist Novel

Output Type: Book Revie

In vitro growth and differentiation of primary myoblasts on thiophene based conducting polymers

Polythiophenes are attractive candidate polymers for use in synthetic cell scaffolds as they are amenable to modification of functional groups as a means by which to increase biocompatibility. In the current study we analysed the physical properties and response of primary myoblasts to three thiophene polymers synthesized from either a basic bithiophene monomer or from one of two different thiophene monomers with alkoxy functional groups. In addition, the effect of the dopants pTS- and ClO4 - was investigated. In general, it was found that pTS- doped polymers were significantly smoother and tended to be more hydrophilic than their ClO 4 - doped counterparts, demonstrating that the choice of dopant significantly affects the polythiophene physical properties. These properties had a significant effect on the response of primary myoblasts to the polymer surfaces; LDH activity measured from cells harvested at 24 and 48 h post-seeding revealed significant differences between numbers of cells attaching to the different thiophene polymers, whilst all of the polymers equally supported cell doubling over the 48 h period. Differences in morphology were also observed, with reduced cell spreading observed on polymers with alkoxy groups. In addition, significant differences were seen in the polymers\u27 ability to support myoblast fusion. In general pTS- doped polymers were better able to support fusion than their ClO4 - doped counterparts. These studies demonstrate that modification of thiophene polymers can be used to promote specific cellular response (e.g. proliferation over differentiation) without the use of biological agents. 2013 The Royal Society of Chemistry

CHIP: Commodity based Hazard Identification Protocol for emerging diseases in plants and animals

This project comprised the development of a commodity-based hazard identification protocol for biological hazards in plants and animals as a decision support tree programmed in Excel. The content of the decision tree is based on the results of a systematic review of pest and pathogen characteristics, a review of risk assessment schemes and on expert judgement. Application of the protocol results in an indication of the level of likelihood of entry of animal and plant pathogens/pests in the area of destination associated with the commodity/pathway, and it guides the decision regarding potential actions to be undertaken in the search for existing and emerging pathogens/pests

Less invasive methods of advanced hemodynamic monitoring: principles, devices, and their role in the perioperative hemodynamic optimization.

The monitoring of the cardiac output (CO) and other hemodynamic parameters, traditionally performed with the thermodilution method via a pulmonary artery catheter (PAC), is now increasingly done with the aid of less invasive and much easier to use devices. When used within the context of a hemodynamic optimization protocol, they can positively influence the outcome in both surgical and non-surgical patient populations. While these monitoring tools have simplified the hemodynamic calculations, they are subject to limitations and can lead to erroneous results if not used properly. In this article we will review the commercially available minimally invasive CO monitoring devices, explore their technical characteristics and describe the limitations that should be taken into consideration when clinical decisions are made